Researchers from the A.A. Baikov Institute of Metallurgy and Materials Science of the Russian Academy of Sciences have created and tested a new component for toothpaste that can restore tooth enamel.

It is based on this compound that bones and teeth are formed in the body of humans and animals. The authors of the work managed to obtain its stable form, which can be used in oral hygiene products. Scientists have developed a technology for producing this component on an industrial scale.

The compound has been tested for effectiveness and safety and could become a non-toxic alternative to fluoride, which is now added to many oral hygiene products.

Destruction of tooth enamel as a result of chemical and mechanical erosion often becomes the cause of dental pathologies.

Kinds of toothpaste with the addition of enamel-restoring compounds are designed to solve this problem.

Thus, hydroxyapatite is often added to pastes for this purpose – it is 97% of bone tissue. As well as fluorine compounds, which in excessive dosage can lead to negative side effects.

Scientists from the Institute of Metallurgy and Metallurgy of the Russian Academy of Sciences have found a new solution to the problem; they have created an additive based on a compound, a precursor of bone tissue, octacalcium phosphate (OCP).

It is known that this compound is the basis for bone formation. Today, OCP is considered by doctors and scientists as a promising material for osteoplasty, and restoration of lost bone tissue. Hydroxyapatite, used in some kinds of toothpaste, is the end product of OCP.

As the researchers explained, for OCP to be used in toothpaste, scientists had to solve the problem of the instability of the compound so that it would not transform into bone hydroxyapatite already in the toothpaste tube, before it was applied to the teeth.

The authors of the work managed to obtain stable forms of OCP that retain their properties in toothpaste until its expiration date.

As the results of laboratory experiments have shown, the rate of restoration of tooth enamel when using OKF is much higher than with the help of hydroxyapatite additives. And unlike another popular remineralizing additive, fluorine compounds, OKF is not toxic.

In addition, the new OCP-based additive can effectively remove bacterial biofilm from the surface of teeth, reduce tooth sensitivity and whiten them. Scientists have also developed a technology for producing the compound in industrial quantities and patented it.

‘A pilot industrial site for the production of the additive has been created at the IMET RAS and negotiations are underway with domestic and foreign manufacturers of oral care products for the use of the additive in their products,’ one of the authors of the development. PLEASE SHARE OUR STORIES

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